一．个人简介

刘娟，博士，博士后，副教授，硕士生导师，药学院/现代中药产业学院中药药理教研室专任教师。主要致力于中药治疗痛经的物质基础及作用机制研究。主持国家自然科学基金青年项目1项，四川省科技厅项目3项，mg老虎机游戏杏林学者项目2项。共发表学术论文30余篇，参与出版专著5部，参编中药药理学教材3部，申请国家发明专利8项（授权4项），获得四川省科技进步奖一等奖1项。现为世界中医药学会联合会道地药材多维评价专业委员会会员、四川省生理科学学会会员。

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二、代表性成果

（一）承担项目

1.国家自然科学基金委员会，青年科学基金项目，82104371，基于PTGFR-IP3/DAG-Ca²⁺通路研究莪术油倍半萜治疗痛经的物质基础及作用机制，2022/01-2024/12，30万，已结题，主持

2. 四川省科学技术厅,自然科学基金面上项目, 2025ZNSFSC0569, 基于MAPK信号通路研究莪术倍半萜治疗原发性痛经的靶点及分子机制, 2025-01至2026-12, 20万元, 在研, 主持

3. 四川省科学技术厅,自然科学基金青年基金项目, 2022NSFSC1332, 莪术治疗痛经新颖倍半萜的发现及其对PTGFR受体通路的影响, 2022-01至2023-12, 10万元,已结题, 主持

4. 四川省科技厅, 科技创新（苗子工程）培育项目, 2019046, 一种缓解痛经症状的川芎脐贴片开发研究, 2019-07至2020-07, 2万元,已结题, 主持

5. mg老虎机游戏, “杏林学者”学科人才科研提升计划青基人才专项, QJRC2022020, 莪术治疗痛经新颖倍半萜的发现及其对PTGFR受体通路的影响, 2022-10至2024-10, 18万元, 在研, 主持

6. mg老虎机游戏, “杏林学者”学科人才科研提升计划, BSH2019028, 川芎治疗痛经的新颖成分的研究与发现, 2019-12至2022-12, 9万元, 结题, 主持

（二）发表论文

1. Juan Liu^#, Ming-Ming Qiao^#, Cheng Peng *,Hong-Zhen Shu, Chun-Wang Meng, Fei Liu* and Liang Xiong*; Curcumanes E and F, two rare sesquiterpenoids with a dicyclo[3.3.1]nonane moiety, from Curcuma longa and their vasorelaxant activities, Frontiers in Chemistry, 2022, 10: 995950.

2. Juan Liu^#, Rui Feng^#, Ou Dai *, Hong Ni, Lu-Si Liu, Hong-Zhen Shu, Yan Lu, Cheng Peng *, Liang Xiong * ; Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle, Phytochemistry, 2022，198,113159.

3. Rui Feng^#, Juan Liu^#, Li Guo*, Hong-Zhen Shu, Qin-Mei Zhou, Li Liu, Cheng Peng *, Liang Xiong *. A pair of new enantiomeric hybrid phthalide–adenines with a rare 5-oxa-1-azaspiro[3,4]octane moiety and two pairs of new enantiomeric hybrid paraethyl phenol–adenines from Ligusticum chuanxiong, Arabian Journal of Chemistry, 2023, 16, 104696.

4. Lei Li^# , Juan Liu^#, Xinrui Li, Yuqin Guo  , Yunqiu Fan , Hongzhen Shu , Guangxu Wu, Cheng Peng* , Liang Xiong*; Sesquiterpenoids from the Florets of Carthamus tinctorius (Safflower) and Their Anti-Atherosclerotic Activity, Nutrients, 2022, 14, 5348.

5. Hong Ni^#; Juan Liu^#; Ou Dai; Rui Feng; Fei Liu; Xiao-Yu Cao; Cheng Peng^*; Liang Xiong^*; Chemical composition and uterine smooth muscle relaxant activity of essential oils from 10 kinds of blood-activating and stasis-resolving Chinese medicinal herbs, Journal of Ethnopharmacology, 2021, 269: 113713.

6. Xin-Rui Li^#; Juan Liu^#; Cheng Peng; Qin-Mei Zhou; Fei Liu; Li Guo* ; Xiong Liang*, Polyacetylene glucosides from the florets of Carthamus tinctorius and their anti-inflammatory activity, Phytochemistry, 2021, 187: 112770.

7. Mei-Ji Sun, Rui Zhao, Min Wen, Chun-Wang Meng, Hai-guo Su, Fu-Xin Mi, Cheng Peng, Juan Liu*, Liang Xiong*，Two new phenolic glycosides from Cyathula officinalis and their relaxant effects on uterine smooth muscle, Phytochemistry Letters, 2025, 66: 100-104.

8. Rui Zhao, Cheng Peng*, Lei Li, Xin-Rui Li, Chun-Wang Meng, Juan Liu*, Liang Xiong*，A new arborinane-type triterpenoid glycoside and three known megastigmanes from the roots of Cyathula officinalis K.C.Kuan，Biochemical Systematics and Ecology, 2022, 104: 104489.

9. Juan Liu; Cheng Peng*; Qin-Mei Zhou; Li Guo; Zhao-Hua Liu; Liang Xiong*; Alkaloids and flavonoid glycosides from the aerial parts of Leonurus japonicus and their opposite effects on uterine smooth muscle, Phytochemistry, 2018, 145: 128-136.

10. Juan Liu; Cheng Peng*; Cheng-Jun He; Jian-Lin Liu; Ya-Cong He; Li Guo; Qin-Mei Zhou; Huai Yang; Liang Xiong*; New amino butenolides from the bulbs of Fritillaria unibracteata, Fitoterapia, 2014, 98: 53-58.

（三）获奖

1. 经产良药益母草的多维评价与开发应用，2017年度四川省科技进步奖，一等奖