一、个人简介

彭伟，博士，博士后，mg老虎机游戏副教授。世界中医药学会联合会翻译专业委员会常务理事、中国民族医药学会方药量效研究分会常务理事、世界中医药学会联合会中药调剂委员会理事、世界中医药学会联合会中药饮片质量专业委员会理事、中国中医药信息会李时珍研究分会理事。Integrative Medicine Discovery主编、Frontiers in Pharmacology 副主编（Ethnopharmacology section）、The Innovation杂志青年编委、中医杂志（英文版）Letter to the editor专栏编辑和青年编委、中草药（英文版）青年编委、西南医科大学学报青年编委。

主要研究方向为中药炮制与制剂、中药及复方药效物质基础与作用机制。主持中国博士后基金、四川省自然科学基金等部省级课题4项、厅局级课题3项、主研国家级/省部级课题8项。以第一或通讯作者在Journal of Advanced Research、Pharmacological Research、Journal of Nanobiotechnology 等杂志发表论文100余篇，被Nature Metabolism等杂志正面引用5000余次， ESI高被引论文9篇。H-index: 39，入选爱思唯尔2023年中国高被引学者（中药学）、2020-2024年全球前2%科学家。授权发明专利4项（成功转化1项），适用新型专利2项，软件著作权1项。

联系方式：成都市温江区柳台大道1166号mg老虎机游戏药学院东耳房

Email: pengwei@cdutcm.edu.cn

二、代表性成果

（一）承担项目

1.“痰瘀伏络”视角下的桂蒌通络方通过“肠道菌群/SCFAs/AMPK/Nrf2”轴调节PAECs铁死亡治疗高原肺动脉高压的作用机制研究，2025/01-2026/12，四川省自然科学基金（No. 2025ZNSFSC0582），负责人，在研。

2.基于线粒体内“钙离子和ROS”稳态研究羟基-α-山椒素对AD神经保护作用的分子机制，2022/01-2023/12，四川省自然科学基金（No. 2022NSFSC0720），负责人，已结题。

3.枝芍药知母汤抑制类风湿关节炎所致骨破坏的物质基础及其机制研究，2019/01-2021/02，四川省科技厅（No. 2019JDRC0074），负责人，已结题。

4.桂枝芍药知母汤抗类风湿关节炎作用物质基础及机制研究，2018/05-2019/12，第63批中国博士后科学基金面上资助（No. 2018M631071），负责人，已结题。

（二）发表论文

1. Qing Zhang; Chengxun He; Juan Guo; Dandan Tang; Die Qian; Chuan Zheng*; Chunjie Wu*; Wei Peng*. Hydroxy-α-sanshool–loaded adipose-targeted mesoporous silica nanoparticles induce white adipose browning and reduce obesity by activating TRPV1. Bio-Design and Manufacturing, 2025, https://doi.org/10.1631/bdm.2400248.

2.Yongqing Cai, Lu Fang, Fei Chen, Peiling Zhong, Xiangru Zheng, Haiyan Xing, Rongrong Fan, Lie Yuan*, Wei Peng*, Xiaoli Li*. Targeting AMPK related signaling pathways: A feasible approach for natural herbal medicines to intervene non-alcoholic fatty liver disease. Journal of Pharmaceutical Analysis, 2025, 15: 101052.

3.Wei Peng^#, Chengxun He^#, Ruolan Li, Die Qian, Lingyu Wang, Wenwen Chen, Qing Zhang*, Chunjie Wu*. Zanthoxylum bungeanum amides ameliorates nonalcoholic fatty liver via regulating gut microbiota and activating AMPK/Nrf2 signaling. Journal of Ethnopharmacology, 2024, 318: 116848.

4.Qing Zhang, Chengxun He, Lingyu Wang, Die Qian, Dandan Tang, Shengnan Jiang, Wenwen Chen, Chunjie Wu*, Wei Peng*. Hydroxy-α-sanshool from the fruits of Zanthoxylum bungeanum Maxim. promotes browning of white fat by activating TRPV1 to induce PPAR-γ deacetylation. Phytomedicine, 2023, 121: 155113.

5.Chengxun He, Ke Wang, Jun Xia, Die Qian, Juan Guo, Lian Zhong, Dandan Tang, Xiuping Chen, Wei Peng*, Yunhui Chen* and Yong Tang*. Natural exosomes-like nanoparticles in mung bean sprouts possesses anti-diabetic effects via activation of PI3K/Akt/GLUT4/GSK-3β signaling pathway. Journal of Nanobiotechnology, 2023, 21:349.

6.Bingke Bai, Chang Liu, Chengzhong Zhang, Xuhui He, Hongrui Wang, Wei Peng*, Chengjian Zheng*. Trichoderma species from plant and soil: An excellent resource for biosynthesis of terpenoids with versatile bioactivities. Journal of Advanced Research, 2023, 49: 81-102.

7.Qi Liang, Jingwen Wang, Yuru Bai, Ruolan Li, Chunjie Wu*, Wei Peng*. Targeting TRPV1 and TRPA1: A feasible strategy for natural herbal medicines to combat postoperative ileus. Pharmacological Research, 2023, 196: 106923.

8.Qing Zhang, Die Qian, Dandan Tang, Jia Liu, Linyu Wang, Wenwen Chen, Chunjie Wu*, Wei Peng*. Glabridin from Glycyrrhiza glabra possesses a therapeutic role against keloid via attenuating PI3K/Akt and transforming growth factor-β1/SMAD signaling pathways. Journal of Agricultural and Food Chemistry, 2022,70(35):10782-10793.

9.Mengmeng Zhang, Daneng Wei, Lin He, Dan Wang, Li Wang, Dandan Tang, Rong Zhao, Xun Ye, Chunjie Wu*, Wei Peng*. Application of response surface methodology (RSM) for optimization of the supercritical CO2 extract of oil from Zanthoxylum bungeanum pericarp: Yield, composition and gastric protective effect. Food Chemistry: X, 2022, 15, 100391.

10.Qing Zhang, Wenwen Chen, Xue Sun, Die Qian, Dandan Tang, Lilin Zhang, Meiyan Li, Linyu Wang, Chunjie Wu*, Wei Peng*. The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers. International Journal of Biological Sciences, 2022, 18(8): 3498-3527.

11.Qing Zhang, Jia Liu, Xinyue Duanhu, Ruolan Li, Wei Peng?, Chunjie Wu?. Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress. Journal of Advanced Research, 2021,34:43-63

12.Huxinyue Duan, Qing Zhang, Jia Liu, Ruolan Li, Dan Wang, Wei Peng*, Chunjie Wu*. Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis. Pharmacological Research, 2021, 168: 105599

13.Yu Long, Qiyue Yang, Yan Xiang, Yulu Zhang, Jinyan Wan, Songyu Liu, Nan Li*, Wei Peng*. Nose to brain drug delivery - a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion. Pharmacological Research 2020, 159: 104795

14.Yulu Zhang, Yu Long, Shuang Yu, Dan Li, Ming Yang, Yongmei Guan, Dingkun Zhang, Jinyan Wan, Songyu Liu, Ai Shi, Nan Li*, Wei Peng*. Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder. Pharmacological Research, 2021, 164: 105376.

15.Mengmeng Zhang#, Mingguo Xie#, Daneng Wei, Li Wang, Meibian Hu, Qing Zhang, Zuxing He, Wei Peng*, Chunjie Wu*. Hydroxy-α-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice. Food & Function, 2019, 10:7315-7324.